

/cdn.vox-cdn.com/uploads/chorus_image/image/64058123/mea_night_0012_Layer_15.0.0.0.1492468155.0.jpg)
Also, the Milky Way could potentially be destroyed by the Reapers if the Refusal ending happened, assuming the Reapers don't find out about the Andromeda Initiative by some means such as indoctrination and hunt them down.And even if they could, galactic society as they know it would possibly be so evolved and unrecognizable that Ryder would be completely culturally isolated. It's also a One-Way Trip, so they can't come back. For Ryder (and, by extension, everyone else on the Tempest), this means that everyone they know and love back home save for their immediate family on the Tempest is now long-dead and forgotten.No matter what choices you made in the past or who you managed to save, Garrus, Tali, Mordin, Ashley, Kaiden, Jack, Miranda, Jacob, Joker, Kasumi, Zaeed, James, Hackett, Wrex, Samara (the latter two because they're both approaching the end of their species' natural lifespans), and just about anyone else you can think of are long since dead and gone by the time Ryder steps out of the cryopod.
MASS EFFECT ANDROMEDA CRACK OPENS ORIGIN SERIES
The fact that, due to the Time Skip nature of the series, all those characters you came to know and love in the original series are dead, with the possible exceptions of Grunt, EDI, Liara, and possibly Javik (depending on Prothean lifespans and Javik's biological age).It's a small touch, but the brief reprise of "Vigil" from the original Mass Effect soundtrack after the end really just serves to push any fan who somehow hadn't shed a tear yet over the edge.We will say goodbye, and you will look back one last time, and know that wherever you go, we will be with you.
